Unilateral isolated choroidal metastasis secondary to squamous cell carcinoma of uterine cervix

Introduction: Cervical cancer is the fourth most common cancer of women worldwide. It spreads either by local invasion or by hematogenous spread. Metastases to the eye, intraocular metastasis have been reported but they are uncommonly seen. Choroidal secondaries are the most common intraocular malignancies in adults, metastasis to the choroid from utero-cervical carcinoma are an exceedingly rare manifestation. Case Report: A 50-year-old female, known case of squamous cell carcinoma of uterine cervix stage ΙΙΙB, post concurrent chemoradiation treated seventeen months back, presented with complaints of unilateral right sided progressive visual impairment since 15 days. After thorough ophthalmic evaluation and fundoscopic examination multiple choroidal masses and posterior exudative retinal detachment were seen in the right eye. Left eye was normal. Hence, diagnosis of choroidal metastasis of right eye was established. Planned on palliative RT and received a dose of 40 Gy in 20 fractions. Result: A month later, there was marginal improvement in the vision of affected eye. Conclusion: The case report demonstrates an unusual but Siddanna R. Palled1, Nihanthy D. S.2, Richa Tiwari2, Surekha Goyal2 Affiliations: 1Associate Professor in Radiation Oncology, Kidwai Memorial Institute of oncology, Bangalore, India; 2Resident in Radiation Oncology, Kidwai Memorial Institute of oncology, Bangalore, India. Corresponding Author: Nihanthy D. S., #15/32, 6th B cross, 2nd C main road, RMV II Stage, Bhoopsandra New Ext, Sanjay Nagar, Bangalore; Karnataka, India, 560094; Email: [email protected] Received: 27 February 2016 Accepted: 14 June 2016 Published: 30 July 2016 PEER REVIEWED | OPEN A CE S possible site of occurrence of metastasis for uterine cervical cancers. The posterior choroid is highly susceptible to disseminated tumor cells compared to the other uveal structures due to its rich vascularity. Orbital metastasis is suggestive of progressive disease, hence early diagnosis and early intervention can save the vision and thus improve the quality of life of the patient.